First saturday of new season with referee appointments
FRIDAY 19 AUGUST
| SATURDAY 20 AUGUST | All 3pm | |||
| Premier | Clyst Valley 1st | Dawlish United 1st | Doherty, Timothy | |
| Premier | Kentisbeare 1st | Alphington 2nd | Wilkins, Scott | |
| Premier | Ottery St Mary Reserves | Crediton United 2nd | Clutterbuck, Richard | |
| Premier | Sidmouth Town 2nd | Elmore 2nd | Thomas, Colin | |
| Division 1 | Beer Albion 2nd | Bow A A C 1st | Dobrijevic, Mark | |
| Division 1 | Hatherleigh Town 1st | East Budleigh 1st | Leahy, Shane | |
| Division 1 | Winkleigh 1st | Newtown 2nd | Smith, Murray | |
| Division 2 | Central 1st | Cranbrook 1st | POSTPONED | |
| Division 2 | Tedburn St Mary 1st | Feniton 2nd | 3.15pm | Ludgate, Reuben |
| Division 2 | Westexe Park Rangers 1st | Dunkeswell Rovers | Smith, Timothy | |
| Division 3 | Halwill 1st | South Zeal United 1sts | Clark, Jonathan | |
| Division 3 | Heavitree United 1sts | Seaton Town 1st | Mann, Keith | |
| Division 3 | Hemyock 1st | Bravehearts 1st | Lloyd, Wayne | |
| Division 3 | Lyme Regis Reserves | Broadclyst 1st | Ebdon, Brinley | |
| Division 3 | Witheridge 1sts | Chagford 1st | Knight, Julie | |
| Division 4 | Budleigh Salterton 2nd | Cullompton Rangers 2nd | Holmes, Brian | |
| Division 4 | Cheriton Fitzpaine 1st | Sidmouth Town 3rd | Turner, Joshua | |
| Division 4 | East Budleigh 2nd | Dawlish United 2nd | England, Ross | |
| Division 4 | St Thomas Social Club 1st | Alphington 3rd | Duncan Stamp | |
| Division 5 | Awliscombe 1st | Thorverton 2nd | Reeby, Brian | |
| Division 5 | Bickleigh 1st | Amory Green Rovers 1st | Clarke, David | |
| Division 5 | Teign Village 1st | Cranbrook United 1st | Everitt, Jason | |
| Division 5 | The Heart of Oak FC 1st | Millwey Rise 1st | Harvey, Brian | |
| Division 6 | Central 2nd | Beacon Knights FC 1st | POSTPONED | |
| Division 6 | Devon Yeoman | Cheriton Fitzpaine 2nd | POSTPONED | |
| Division 6 | Dolton Rangers AFC 1st | Ottery St Mary Dev XI | Rose, David | |
| Division 6 | Okehampton Argyle 3rd | City Raiders AFC 1st | Gary Sharpe | |
| Division 7 | City Raiders AFC 2nd | Exeter Royals 1st | Chamberlain, Jason | |
| Division 7 | Newton St Cyres 2nd | Bradninch 1st | POSTPONED | |
| Division 7 | Otterton 1st | Exmouth Rovers 1st | Beresford, David | |
| Division 7 | Phoenix United 1st | Hatherleigh Town 2nd | Jacques, Neil | |
| Division 7 | Seaton Town 2nd | Priory 1st | Roberts, Peter | |
| Division 7 | Whipton & Pinhoe 2nd | Westexe Park Rgrs 2nds | POSTPONED | |
| Division 8 | Tedburn St Mary 2nds | Ex Dons | Palfrey, Stuart | |
| Division 8 | Farway United 2nd | Hemyock 2nd | Taylor, Colin | |
| Division 8 | Lympstone 2nd | North Tawton 1st | Phil Willer | |
| Division 8 | South Zeal United 2nds | Amory Green Rovers 2nd | POSTPONED | |
Saturday 20th August 2022